Synthetic Transcription Factor And Uses Thereof
Synthetic Transcription Factor And Uses Thereof
Description
Abstract:
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- The present invention provides for a synthetic transcription factor (TF) comprising a first peptide capable of binding a target ligand, a second peptide capable of binding a target DNA, and a peptide linker linking the first and second peptides. The present invention also provide for a system for modulating the mutagenesis frequency of a host cell. The host cell has a mutator rate (R) which is inversely proportional to a phenotypic trait (P).
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Issue/Publication date:
12/10/2015
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