Identification Of Discriminant Proteins Through Antibody Profiling, Methods And Apparatus For Identifying An Individual
Identification Of Discriminant Proteins Through Antibody Profiling, Methods And Apparatus For Identifying An Individual
Description
Abstract:
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- A method for determining a plurality of proteins for discriminating and positively identifying an individual based from a biological sample. The method may include profiling a biological sample from a plurality of individuals against a protein array including a plurality of proteins. The protein array may include proteins attached to a support in a preselected pattern such that locations of the proteins are known. The biological sample may be contacted with the protein array such that a portion of antibodies in the biological sample reacts with and binds to the proteins forming immune complexes. A statistical analysis method, such as discriminant analysis, may be performed to determine discriminating proteins for distinguishing individuals. Proteins of interest may be used to form a protein array. Such a protein array may be used, for example, to compare a forensic sample from an unknown source with a sample from a known source.
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Issue/Publication date:
| 03/03/2015 |
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