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Hybridization And Sequencing Of Nucleic Acids Using Base Pair Mismatches

Hybridization And Sequencing Of Nucleic Acids Using Base Pair Mismatches

Description

Abstract:

Devices and techniques for hybridization of nucleic acids and for determining the sequence of nucleic acids. Arrays of nucleic acids are formed by techniques, preferably high resolution, light-directed techniques. Positions of hybridization of a target nucleic acid are determined by, e.g., epifluorescence microscopy. Devices and techniques are proposed to determine the sequence of a target nucleic acid more efficiently and more quickly through such synthesis and detection techniques.

Issue/Publication date:

09/04/2001

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